Clinical Atlas of Interstitial Lung Disease

Clinical Atlas of Interstitial Lung Disease

Interstitial lung disease (ILD) is a common term that includes over 130 chronic lung disorders. The lung is affected in three ways: the tissue is damaged; the walls of the air sacs become inflamed; and scarring (or fibrosis) begins in the interstitium. Breathlessness during exercise is one of the initial symptoms. A dry cough may also be present. Different types of ILD may create the same kind of symptoms which may vary in severity. The common link between the many forms of ILD is that they all begin with inflammation. The inflammation may affect different parts of the lung. Inflammation of these parts may heal or may lead to permanent scarring of the lung tissue. The level of disability that a person experiences depends on the amount of scarring. Clinical Atlas of Interstitial Lung Disease represents a complete and comprehensive visual representation of the disease. It is a true pictorial supplement to the numerous monographs and texts on the topic.

The interstitial lung diseases, also called diffuse parenchymal lung diseases, are a diverse group of pulmonary disorders classified together because of similar clinical, roentgenographic, physiologic, or pathologic features. During the past 50 years, we have experienced remarkable advances in the classification, diagnosis, and management of these diseases. Technological advances, particularly high-resolution computed tomography, bronchoalveolar lavage, and video-assisted thoracic surgery, have provided access to information that has vastly improved our understanding of these entities. In addition, genetic medicine, the use of new technologies (e.g., microarrays, mass spectroscopic analysis of proteins, and laser capture microdissection) and the development of animal models have led to better understanding of the pathogenesis of these disorders.
Unfortunately, patients with diffuse parenchymal lung disease continue to present a difficult diagnostic and management challenge to clinicians. A major reason is that the topic of “interstitial lung disease” is vast and difficult to grasp. Some 25 years ago when I first became interested in interstitial lung diseases, there was no ready source of information relating specifically to these processes. Even today, there is a need for a comprehensive, yet easy to read, manual of the key information about the important interstitial lung diseases.
The purpose of this atlas is to provide the clinician, from medical student to lung specialist, with a ready reference helpful in their attempts to master this topic and to provide guidance in their daily practice. The subject of interstitial lung disease is inherently multidisciplinary; consequently, the authors have provided a consistent approach to each entity that includes the key clinical, physiologic, radiologic, and pathologic features.
The Clinical Atlas of Interstitial Lung Disease is composed of 37 chapters loosely divided into six sections. The first section provides a historical background to the interstitial lung diseases and an overview of the basis for recognizing the key features that allow a specific diagnosis to be achieved. The second section is dedicated to the interstitial lung diseases of unknown etiology, including sarcoidosis, the idiopathic interstitial pneumonias, and eosinophilic pneumonias. The third section describes interstitial lung diseases of known etiology (e.g., drug-induced, radiation, hypersensitivity pneumonitis, and pneumoconioses). The fourth section addresses interstitial lung diseases associated with the connective tissue diseases and pulmonary vasculitidies. The fifth section deals with a number of specific entities (e.g., alveolar proteinosis, lymphangioleiomyomatosis, and Langerhans cell histiocytosis). The final section devotes several chapters to the pulmonary manifestations of systemic diseases, such as paraproteinemias, liver and gastrointestinal disease, and malignancy.
We owe a debt of gratitude to all those who were involved in producing this Clinical Atlas of Interstitial Lung Disease. The authors have succeeded in creating a readable, concise atlas that is up to date and user friendly

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